Tissue expression profile of ACE2

02 Apr 2020

Tissue expression of ACE2


COVID-19 is not only a respiratory disease, it affects multiple organs and also the immune system. To better understand the various manifestations and modes of activity of the disease, we visualized the expression of the ACE2 receptor across more than 400 tissues and cell types.


Top 30 human tissues and cell-types with highest ACE2 expression

Data selected: mRNASeq samples from adult, healthy untreated subjects

post thumb Figure: GENEVESTIGATOR® Anatomy plot showing ACE2 expression in the top 30 of 445 tissues and cell types tested.


Top 30 human tissues and cell-types with highest TMPRSS2 expression

Data selected: mRNASeq samples from adult, healthy untreated subjects

post thumb

Figure: GENEVESTIGATOR® Anatomy plot showing TMPRSS2 expression in the top 30 of 445 tissues and cell types tested.

An extended visualization of ACE2 and TMPRSS2 across all 445 tissues and cell types is shown here: